PAMAM Dendrimer G4.5 Caboxylate Sodium Salt Dendritech G4.5...

来自 : www.bioport.cn/product-4074019 发布时间：2021-03-24

PAMAM Dendrimers

Polyamidoamine (PAMAM) dendrimers are hyperbranched polymers with unparalleled molecular uniformity, narrow molecular weight distribution, defined size and shape characteristics and a multifunctional terminal surface. These nanoscale polymers consist of an ethylenediamine core, a repetitive branching amidoamine internal structure and a primary amine terminal surface. Dendrimers are “grown” off a central core in an iterative manufacturing process, with each subsequent step representing a new “generation” of dendrimer. Increasing generations (molecular weight) produce larger molecular diameters, twice the number of reactive surface sites, and approximately double the molecular weight of the preceding generation. PAMAM dendrimers also assume a spheroidal, globular shape at Generation 4 and above (see molecular simulation below). Their functionality is readily tailored, and their uniformity, size and highly reactive “molecular Velcro” surfaces are the functional keys to their use.

Generation 2 PAMAM Dendrimer
(Clickfor larger view)Dendrimer Terminal Group
(Clickfor larger view)

The term \"dendrimer\" was derived from its tree-like branching structure. The tables below show the calculated properties* ofprimary aminesurface PAMAM dendrimers by generation, followed by common alternative surfaces. For mixed surfaces or other customized dendrimers, please inquire.

GenerationMolecular WeightMeasured Diameter (Å)Surface Groups

0

517

15

4

1

1,430

22

8

2

3,256

29

16

3

6,909

36

32

4

14,215

45

64

5

28,826

54

128

6

58,048

67

256

7

116,493

81

512

8

233,383

97

1024

9

467,162

114

2048

10

934,720

135

4096

*Theoretical Properties, not to be used as specifications.

GenerationMolecular
Weight*End Groups*HYDROXY SURFACE PAMAMPAMAM Dendrimer G2-OH327216PAMAM Dendrimer G3-OH694132PAMAM Dendrimer G4-OH1427964PAMAM Dendrimer G5-OH28954128PAMAM Dendrimer G6-OH58304256PAMAM Dendrimer G7-OH117005512SUCCINAMIC ACID SURFACE PAMAMPAMAM Dendrimer G2-SA Succinamic acid485616PAMAM Dendrimer G3-SA Succinamic acid1010932PAMAM Dendrimer G4-SA Succinamic acid2061564PAMAM Dendrimer G5-SA Succinamic acid41626128PAMAM Dendrimer G6-SA Succinamic acid83648256SODIUM CARBOXYLATE SURFACE PAMAMPAMAM Dendrimer G0.5 Caboxylate Sodium Salt12698PAMAM Dendrimer G1.5 Caboxylate Sodium Salt293516PAMAM Dendrimer G2.5 Caboxylate Sodium Salt626732PAMAM Dendrimer G3.5 Caboxylate Sodium Salt1293164PAMAM Dendrimer G4.5 Caboxylate Sodium Salt26258128PAMAM Dendrimer G5.5 Caboxylate Sodium Salt52913256PAMAM Dendrimer G6.5 Caboxylate Sodium Salt106222512PAMAM Dendrimer G7.5 Caboxylate Sodium Salt2128411024HYDROPHOBE SUBSTITUTED PAMAMPAMAM Dendrimer G2-25% C12 Hydrophobe4730Mixed amine/hydrophobePAMAM Dendrimer G2-50% C12 Hydrophobe6205Mixed amine/hydrophobePAMAM Dendrimer G3-25% C12 Hydrophobe9857Mixed amine/hydrophobePAMAM Dendrimer G3-50% C12 Hydrophobe12807Mixed amine/hydrophobePAMAM Dendrimer G4-25% C12 Hydrophobe20112Mixed amine/hydrophobePAMAM Dendrimer G4-50% C12 Hydrophobe26010Mixed amine/hydrophobe

Note: Hydrophobe substituted is average molecular weight and average substitution; statistical distributions are obtained.

Below: The step-growth reaction of EDA to Generation 5 PAMAM Dendrimer

联系我们时，请说明是在生物港上看到的，谢谢。